Emerging perspectives in perioperative use of gabapentinoids.

In Reply: We would like to thank Drs. van Schalkwyk and Kachhwah et al. for their comments concerning our article.1 Dr. van Schalkwyk reports that our statement “gabapentinoids are very well tolerated” is “an assertion contradicted by even the most enthusiastic of the three old meta-analyses [we] cite.” Our article cites five, not three, meta-analyses.2–6 These were not old, but were the most recent meta-analyses on perioperative gabapentinoids available at the time of our writing the review, with two having been published in 2006 and the Emerging Perspectives in Perioperative Use of Gabapentinoids